Drug Development & Regulation

International Nonproprietary Name INN

TRUluslararası Mülkiyete Konu Olmayan İsim
Also known as:Generic name · Nonproprietary name

A unique, globally recognized generic name assigned by the World Health Organization to a pharmaceutical substance, which is public property and cannot be registered as a trademark.

In depth

The WHO INN program selects names in consultation with national nomenclature bodies. Names share common stems indicating pharmacological class, for example -olol (β-blockers), -pril (ACE inhibitors), -sartan (angiotensin II receptor antagonists), -vastatin (HMG-CoA reductase inhibitors) and -tinib (tyrosine kinase inhibitors).

Some national names differ from the INN, such as acetaminophen (USAN) for paracetamol. Salts and esters are named by combining the INN with the salt or ester moiety (e.g., metoprolol tartrate). Regulatory documents, SmPCs and prescribing systems use the INN as the common name of the active substance.

Clinical pearl

Prescribing by INN reduces confusion between brands and supports generic substitution; knowing both INN and national names (e.g., paracetamol/acetaminophen) helps prevent inadvertent duplicate therapy.

Example drugs

Metoprolol Enalapril Losartan Atorvastatin Imatinib paracetamol
TRIn Turkish

Uluslararası Mülkiyete Konu Olmayan İsim

Dünya Sağlık Örgütü tarafından bir farmasötik maddeye verilen, küresel olarak tanınan, kamu malı niteliğindeki ve ticari marka olarak tescil edilemeyen benzersiz jenerik isimdir.

DSÖ INN programı isimleri ulusal adlandırma kuruluşlarıyla iş birliği içinde seçer. İsimler farmakolojik sınıfı gösteren ortak kökler taşır; örneğin -olol (beta blokörler), -pril (ACE inhibitörleri), -sartan (anjiyotensin II reseptör antagonistleri), -vastatin (HMG-KoA redüktaz inhibitörleri) ve -tinib (tirozin kinaz inhibitörleri).

Bazı ulusal isimler INN adından farklıdır; örneğin parasetamol ABD'de asetaminofen (USAN) olarak adlandırılır. Tuz ve esterler, INN adının tuz veya ester kısmıyla birleştirilmesiyle adlandırılır (örneğin metoprolol tartarat). Ruhsat belgeleri, KÜB'ler ve reçete sistemleri etkin maddenin ortak adı olarak INN adını kullanır.

INN ile reçeteleme ticari isimler arasındaki karışıklığı azaltır ve jenerik ikameyi kolaylaştırır; INN ile ulusal isimlerin (örneğin parasetamol/asetaminofen) birlikte bilinmesi istenmeden yapılan mükerrer tedaviyi önlemeye yardımcı olur.

Diğer adları:Jenerik ad · Ortak isim · Etkin madde adı
Updated 24.09.2026 0 views Educational reference — verify against current sources before clinical use.

Read next

ATC Classification SystemATC Sınıflandırma Sistemi

The WHO system that classifies active substances into five hierarchical levels according to the organ or system on which they act and their therapeutic, pharmacological and chemical properties.

 Generic DrugJenerik İlaç

A medicinal product with the same qualitative and quantitative composition in active substance(s) and the same pharmaceutical form as a reference product, whose bioequivalence with that product has been demonstrated.

 Active Pharmaceutical IngredientEtkin Madde

The substance in a medicinal product that is responsible for its pharmacological activity, as distinct from the excipients; in manufacturing terms it is the drug substance produced under GMP.

 Salt FormTuz Formu

A form of an ionisable drug substance combined with a pharmaceutically acceptable counterion, such as hydrochloride, sodium, maleate or mesilate, chosen to improve solubility, stability, crystallinity or manufacturability.

 Medication Errorİlaç Hatası

Any preventable event that may cause or lead to inappropriate medication use or patient harm while the medication is in the control of a healthcare professional, patient or consumer.

 Drugİlaç

A substance or product used, or intended for use, to modify or explore physiological systems or pathological states for the benefit of the recipient, that is, to prevent, diagnose, treat or relieve disease.