Drug Development & Regulation

ATC Classification System ATC

TRATC Sınıflandırma Sistemi
Also known as:Anatomical Therapeutic Chemical classification · ATC/DDD system · ATC code

The WHO system that classifies active substances into five hierarchical levels according to the organ or system on which they act and their therapeutic, pharmacological and chemical properties.

In depth

Anatomical Therapeutic Chemical codes are maintained by the WHO Collaborating Centre for Drug Statistics Methodology. Level 1 is the anatomical main group (one letter, 14 groups), level 2 the therapeutic subgroup, levels 3 and 4 pharmacological/chemical subgroups and level 5 the chemical substance: metformin is A10BA02 (A alimentary tract and metabolism, A10 drugs used in diabetes, A10B blood glucose lowering drugs excluding insulins, A10BA biguanides).

It is used with the defined daily dose (DDD), the assumed average maintenance dose per day for a drug's main indication in adults, in drug utilization research and for comparing consumption between settings.

Clinical pearl

Shared ATC level-4 codes can flag therapeutic duplication during prescription review; one substance may have several codes by use, e.g., acetylsalicylic acid B01AC06 (antiplatelet) and N02BA01 (analgesic).

Example drugs

Metformin Acetylsalicylic acid
TRIn Turkish

ATC Sınıflandırma Sistemi

Etkin maddeleri, etki ettikleri organ ya da sisteme ve terapötik, farmakolojik ve kimyasal özelliklerine göre beş basamaklı hiyerarşik bir yapıda sınıflandıran DSÖ sistemidir.

Anatomik Terapötik Kimyasal (ATC) kodları, DSÖ İlaç İstatistikleri Metodolojisi İşbirliği Merkezi tarafından yönetilir. 1. düzey anatomik ana grup (tek harf, 14 grup), 2. düzey terapötik alt grup, 3. ve 4. düzeyler farmakolojik/kimyasal alt gruplar, 5. düzey ise kimyasal maddedir: metformin A10BA02 koduna sahiptir (A sindirim sistemi ve metabolizma, A10 diyabette kullanılan ilaçlar, A10B insülinler hariç kan şekerini düşüren ilaçlar, A10BA biguanidler).

Sistem, bir ilacın ana endikasyonunda erişkinlerdeki varsayılan ortalama günlük idame dozu olan tanımlanmış günlük doz (DDD) ile birlikte ilaç kullanım araştırmalarında ve farklı ortamlardaki tüketimin karşılaştırılmasında kullanılır.

Aynı 4. düzey ATC kodunu paylaşan ilaçlar reçete incelemesinde terapötik duplikasyona işaret edebilir; bir madde kullanımına göre birden fazla koda sahip olabilir, örneğin asetilsalisilik asit B01AC06 (antiplatelet) ve N02BA01 (analjezik).

Diğer adları:Anatomik Terapötik Kimyasal Sınıflandırma Sistemi · ATC kodu
Updated 24.09.2026 0 views Educational reference — verify against current sources before clinical use.

Read next

International Nonproprietary NameUluslararası Mülkiyete Konu Olmayan İsim

A unique, globally recognized generic name assigned by the World Health Organization to a pharmaceutical substance, which is public property and cannot be registered as a trademark.

 Therapeutic DuplicationTerapötik Duplikasyon

The unintended concurrent use of two or more drugs with the same active ingredient, the same pharmacological class or overlapping mechanisms for the same indication, without added benefit.

 Mechanism of ActionEtki Mekanizması

The specific biochemical interaction through which a drug produces its pharmacological effect, usually binding to a defined molecular target such as a receptor, enzyme, ion channel or transporter.

 IndicationEndikasyon

A disease, condition or clinical situation in which the use of a drug is appropriate; approved indications are those accepted by the regulator and stated in the product's authorised information.

 PolypharmacyPolifarmasi

The concurrent use of multiple medicines by one patient, most often defined as five or more regular medicines, which may be appropriate or problematic.