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In Progress: Binimetinib Pathway, Pharmacokinetics/Pharmacodynamics

PA166364581 Last updated February 2025 Caroline F. Thorn
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Conditions
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Reactions
In Progress: Binimetinib Pathway, Pharmacokinetics/Pharmacodynamics pathway diagram
In Progress: Binimetinib Pathway, Pharmacokinetics/Pharmacodynamics — pathway diagram from PharmGKB / ClinPGx
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Reactions & interactions (7)

  • Biochemical Reaction
    binimetinib → binimetinib glucuronide
  • Biochemical Reaction
    binimetinib → N-desmethyl binimetinib
  • Catalysis
    UGT1A1 → Biochemical Reaction
  • Catalysis
    CYP1A2 → Biochemical Reaction
  • Catalysis
    CYP2C19 → Biochemical Reaction
  • Inhibition
    binimetinib → MAP2K2
  • Inhibition
    binimetinib → MAP2K1

Edit history (1)

  • 2025-02-03 Create
In Progress: Binimetinib Pathway, Pharmacokinetics/Pharmacodynamics pathway diagram (enlarged)