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PharmGKB · ClinPGx

In Progress: Berberine Pathway, Pharmacokinetics

PA166358641 Last updated November 2024 Caroline F. Thorn
1/8
Drugs & chemicals
0
Genes
0/0
Conditions
16
Reactions
In Progress: Berberine Pathway, Pharmacokinetics pathway diagram
In Progress: Berberine Pathway, Pharmacokinetics — pathway diagram from PharmGKB / ClinPGx
Click to enlarge

Reactions & interactions (16)

  • Biochemical Reaction
    berberine → demethyleneberberine
  • Biochemical Reaction
    jatrorrhizine → jatrorrhizine 3-O-glucuronide
  • Biochemical Reaction
    berberrubine → berberrubine 9-O-glucuronide
  • Biochemical Reaction
    berberine → jatrorrhizine
  • Biochemical Reaction
    berberrubine → thalifendine 10-O-glucuronide
  • Biochemical Reaction
    demethyleneberberine → demethyleneberberine 2-O-sulfate
  • Biochemical Reaction
    berberine → berberrubine
  • Catalysis
    CYP2E1 → Biochemical Reaction
  • Catalysis
    CYP1A2 → Biochemical Reaction
  • Catalysis
    CYP3A4 → Biochemical Reaction
  • Catalysis
    CYP2D6 → Biochemical Reaction
  • Catalysis
    CYP2C19 → Biochemical Reaction
  • Catalysis
    SLC22A1 → Transport
  • Catalysis
    CYP2D6 → Biochemical Reaction
  • Catalysis
    CYP1A2 → Biochemical Reaction
  • Transport
    berberine → berberine

Edit history (3)

  • 2024-11-14 Create
  • 2024-11-14 Update Added drug class code
  • 2024-11-14 Update Added summary
In Progress: Berberine Pathway, Pharmacokinetics pathway diagram (enlarged)