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PharmGKB · ClinPGx

In Progress: Sotorasib Pathway, Pharmacokinetics/Pharmacodynamics

PA166416801 Last updated August 2025 Caroline F. Thorn
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Drugs & chemicals
1
Genes
0/0
Conditions
7
Reactions
In Progress: Sotorasib Pathway, Pharmacokinetics/Pharmacodynamics pathway diagram
In Progress: Sotorasib Pathway, Pharmacokinetics/Pharmacodynamics — pathway diagram from PharmGKB / ClinPGx
Click to enlarge

Reactions & interactions (7)

  • Biochemical Reaction
    sotorasib → sotorasib m18
  • Biochemical Reaction
    sotorasib → sotorasib m10
  • Biochemical Reaction
    sotorasib → sotorasib m24
  • Catalysis
    CYP2C8 → Biochemical Reaction
  • Catalysis
    GGTs → Biochemical Reaction
  • Catalysis
    CYP3A4 → Biochemical Reaction
  • Inhibition
    sotorasib → KRAS

Edit history (1)

  • 2025-08-26 Create
In Progress: Sotorasib Pathway, Pharmacokinetics/Pharmacodynamics pathway diagram (enlarged)