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PharmGKB · ClinPGx

In Progress: Abrocitinib Pathway, Pharmacokinetics

PA166350141 Last updated September 2024 Caroline F. Thorn
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Conditions
18
Reactions
In Progress: Abrocitinib Pathway, Pharmacokinetics pathway diagram
In Progress: Abrocitinib Pathway, Pharmacokinetics — pathway diagram from PharmGKB / ClinPGx
Click to enlarge

Reactions & interactions (18)

  • Biochemical Reaction
    abrocitinib → abrocitinib metabolite m1
  • Biochemical Reaction
    abrocitinib → abrocitinib metabolite m2
  • Biochemical Reaction
    abrocitinib → abrocitinib metabolite m4
  • Catalysis
    CYP2B6 → Biochemical Reaction
  • Catalysis
    CYP2C9 → Biochemical Reaction
  • Catalysis
    CYP3A4 → Biochemical Reaction
  • Catalysis
    CYP2C19 → Biochemical Reaction
  • Catalysis
    SLC22A8 → Transport
  • Catalysis
    CYP2C9 → Biochemical Reaction
  • Catalysis
    CYP2C19 → Biochemical Reaction
  • Catalysis
    SLC22A8 → Transport
  • Catalysis
    CYP3A4 → Biochemical Reaction
  • Catalysis
    CYP2C19 → Biochemical Reaction
  • Catalysis
    CYP2C9 → Biochemical Reaction
  • Catalysis
    SLC22A8 → Transport
  • Transport
    abrocitinib metabolite m1 → abrocitinib metabolite m1
  • Transport
    abrocitinib metabolite m2 → abrocitinib metabolite m2
  • Transport
    abrocitinib metabolite m4 → abrocitinib metabolite m4

Edit history (1)

  • 2024-09-03 Create
In Progress: Abrocitinib Pathway, Pharmacokinetics pathway diagram (enlarged)