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PharmGKB · ClinPGx

In Progress: Aflatoxin b Pathway, Pharmacokinetics

PA166343221 Last updated July 2024 Caroline F. Thorn
1/9
Drugs & chemicals
0
Genes
2/2
Conditions
17
Reactions
In Progress: Aflatoxin b Pathway, Pharmacokinetics pathway diagram
In Progress: Aflatoxin b Pathway, Pharmacokinetics — pathway diagram from PharmGKB / ClinPGx
Click to enlarge

Reactions & interactions (17)

  • Activation
    efavirenz → CYP3A4
  • Biochemical Reaction
    aflatoxicol → aflatoxicol h1
  • Biochemical Reaction
    aflatoxin b1 → aflatoxin-m1-8,9-epoxide
  • Biochemical Reaction
    aflatoxicol h1 → aflatoxin q1
  • Biochemical Reaction
    aflatoxin b1 → aflatoxin p1
  • Biochemical Reaction
    aflatoxin b1 → aflatoxicol
  • Biochemical Reaction
    aflatoxin b1 → aflatoxin m1
  • Biochemical Reaction
    aflatoxin b1 → aflatoxin q1
  • Biochemical Reaction
    aflatoxin-m1-8,9-epoxide → aflatoxin b1 dialcohol
  • Catalysis
    CYP3A4 → Biochemical Reaction
  • Catalysis
    CYP1A2 → Biochemical Reaction
  • Catalysis
    CYP2A13 → Biochemical Reaction
  • Catalysis
    CYP1A2 → Biochemical Reaction
  • Catalysis
    CYP3A5 → Biochemical Reaction
  • Catalysis
    CYP3A4 → Biochemical Reaction
  • Leads To
    aflatoxin-m1-8,9-epoxide → Neoplasms
  • Leads To
    aflatoxin-m1-8,9-epoxide → Drug Toxicity

Edit history (1)

  • 2024-07-05 Create
In Progress: Aflatoxin b Pathway, Pharmacokinetics pathway diagram (enlarged)