About this pathway
Work in progress...
Reactions & interactions (27)
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Biochemical Reaction
cabozantinib → cabozantinib n-oxide
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Biochemical Reaction
cabozantinib → cabozantinib metabolite m7
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Biochemical Reaction
cabozantinib metabolite m7 → cabozantinib metabolite m2a
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Biochemical Reaction
cabozantinib → cabozantinib metabolite m9
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Catalysis
ABCC2 → Transport
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Catalysis
ABCG2 → Transport
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Catalysis
SLCO1B1 → Transport
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Catalysis
SLCO1B3 → Transport
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Catalysis
ABCC2 → Transport
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Catalysis
CYP2C9 → Biochemical Reaction
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Catalysis
CYP3A4 → Biochemical Reaction
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Inhibition
cabozantinib n-oxide → CYP2C8
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Inhibition
cabozantinib → MET
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Inhibition
cabozantinib → CYP2C8
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Inhibition
cabozantinib → AXL
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Inhibition
cabozantinib metabolite m2a → SLC22A6
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Inhibition
cabozantinib → KDR
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Inhibition
cabozantinib → ABCB1
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Inhibition
cabozantinib → SLC47A2
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Inhibition
cabozantinib metabolite m2a → SLC47A2
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Inhibition
cabozantinib → RET
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Inhibition
cabozantinib metabolite m2a → ABCB11
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Inhibition
cabozantinib → SLC47A1
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Inhibition
cabozantinib metabolite m2a → SLC22A8
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Inhibition
cabozantinib metabolite m2a → SLC47A1
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Transport
cabozantinib → cabozantinib
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Transport
cabozantinib metabolite m2a → cabozantinib metabolite m2a
Edit history (1)
- 2023-07-17 Create