All PharmGKB pathways
PharmGKB · ClinPGx

In Progress: Dabigatran Pathway, Pharmacokinetics/Pharmacodynamics

PA166306081 Last updated July 2023 Caroline F. Thorn
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Drugs & chemicals
1
Genes
0/0
Conditions
10
Reactions
In Progress: Dabigatran Pathway, Pharmacokinetics/Pharmacodynamics pathway diagram
In Progress: Dabigatran Pathway, Pharmacokinetics/Pharmacodynamics — pathway diagram from PharmGKB / ClinPGx
Click to enlarge

About this pathway

Work in progress.

Reactions & interactions (10)

  • Biochemical Reaction
    dabigatran → dabigatran glucuronide
  • Biochemical Reaction
    dabigatran etexilate → dabigatran
  • Catalysis
    UGT2B15 → Biochemical Reaction
  • Catalysis
    UGT2B7 → Biochemical Reaction
  • Catalysis
    UGT1A9 → Biochemical Reaction
  • Catalysis
    CES2 → Biochemical Reaction
  • Catalysis
    CES1 → Biochemical Reaction
  • Inhibition
    dabigatran → thrombin
  • Inhibition
    idarucizumab → dabigatran
  • Leads To
    F2 → thrombin

Edit history (2)

  • 2023-07-03 Create
  • 2023-07-13 Update Added related pathways
In Progress: Dabigatran Pathway, Pharmacokinetics/Pharmacodynamics pathway diagram (enlarged)