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In Progress: Brigatinib Pathway, Pharmacokinetics/Pharmacodynamics

PA166305241 Last updated June 2023 Caroline F. Thorn
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In Progress: Brigatinib Pathway, Pharmacokinetics/Pharmacodynamics pathway diagram
In Progress: Brigatinib Pathway, Pharmacokinetics/Pharmacodynamics — pathway diagram from PharmGKB / ClinPGx
Click to enlarge

About this pathway

Work in progress.

Reactions & interactions (5)

  • Biochemical Reaction
    brigatinib → n-demethyl brigatinib
  • Catalysis
    CYP3A4 → Biochemical Reaction
  • Catalysis
    CYP2C8 → Biochemical Reaction
  • Inhibition
    n-demethyl brigatinib → ALK
  • Inhibition
    brigatinib → ALK

Edit history (1)

  • 2023-06-21 Create
In Progress: Brigatinib Pathway, Pharmacokinetics/Pharmacodynamics pathway diagram (enlarged)