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PharmGKB · ClinPGx

In Progress: Apixaban Pathway, Pharmacokinetics/Pharmacodynamics

PA166280641 Last updated June 2023 Caroline F. Thorn
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In Progress: Apixaban Pathway, Pharmacokinetics/Pharmacodynamics pathway diagram
In Progress: Apixaban Pathway, Pharmacokinetics/Pharmacodynamics — pathway diagram from PharmGKB / ClinPGx
Click to enlarge

About this pathway

Work in progress

Reactions & interactions (9)

  • Biochemical Reaction
    o-demethyl apixaban → o-demethyl apixaban sulfate
  • Biochemical Reaction
    apixaban → o-demethyl apixaban
  • Catalysis
    ABCB1 → Transport
  • Catalysis
    ABCG2 → Transport
  • Catalysis
    SULT1A1 → Biochemical Reaction
  • Catalysis
    CYP3A5 → Biochemical Reaction
  • Catalysis
    CYP3A4 → Biochemical Reaction
  • Inhibition
    apixaban → F10
  • Transport
    apixaban → apixaban

Edit history (3)

  • 2022-10-17 Create
  • 2023-06-20 Update Fixed typo in pathway name in gpml
  • 2023-06-20 Update Fixed typo in drug name in summary
In Progress: Apixaban Pathway, Pharmacokinetics/Pharmacodynamics pathway diagram (enlarged)