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PharmGKB · ClinPGx

In progress: Buprenorphine Pathway, Pharmacokinetics

PA166301282 Last updated May 2023 Caroline F. Thorn
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Drugs & chemicals
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Genes
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Conditions
12
Reactions
In progress: Buprenorphine Pathway, Pharmacokinetics pathway diagram
In progress: Buprenorphine Pathway, Pharmacokinetics — pathway diagram from PharmGKB / ClinPGx
Click to enlarge

About this pathway

Work in progress.

Reactions & interactions (12)

  • Biochemical Reaction
    buprenorphine → norbuprenorphine
  • Biochemical Reaction
    buprenorphine → buprenorphine 3-glucuronide
  • Biochemical Reaction
    norbuprenorphine → norbuprenorphine glucuronide
  • Catalysis
    CYP2C8 → Biochemical Reaction
  • Catalysis
    CYP3A4 → Biochemical Reaction
  • Catalysis
    CYP3A7 → Biochemical Reaction
  • Catalysis
    CYP3A5 → Biochemical Reaction
  • Catalysis
    UGT1A3 → Biochemical Reaction
  • Catalysis
    UGT1A1 → Biochemical Reaction
  • Catalysis
    UGT2B7 → Biochemical Reaction
  • Catalysis
    UGT1A1 → Biochemical Reaction
  • Catalysis
    UGT1A3 → Biochemical Reaction

Edit history (1)

  • 2023-05-09 Create
In progress: Buprenorphine Pathway, Pharmacokinetics pathway diagram (enlarged)