In Progress: Regorafenib Pathway, Pharmacokinetics

About this pathway

Reactions & interactions (17)

• Biochemical Reaction
  desmethyl regorafenib → n-desmethyl regorafenib n-oxide
• Biochemical Reaction
  regorafenib → regorafenib N-oxide
• Biochemical Reaction
  regorafenib → regorafenib metabolite m3
• Biochemical Reaction
  regorafenib N-oxide → regorafenib metabolite m8
• Biochemical Reaction
  regorafenib N-oxide → n-desmethyl regorafenib n-oxide
• Biochemical Reaction
  n-desmethyl regorafenib n-oxide → desmethyl regorafenib
• Biochemical Reaction
  regorafenib → regorafenib glucuronide
• Biochemical Reaction
  regorafenib metabolite m3 → desmethyl regorafenib
• Biochemical Reaction
  regorafenib N-oxide → regorafenib
• Biochemical Reaction
  regorafenib metabolite m8 → regorafenib glucuronide
• Catalysis
  CYP3A4 → Biochemical Reaction
• Catalysis
  CYP3A4 → Biochemical Reaction
• Catalysis
  CYP3A4 → Biochemical Reaction
• Catalysis
  CYP2J2 → Biochemical Reaction
• Catalysis
  UGT1A9 → Biochemical Reaction
• Catalysis
  UGT1A9 → Biochemical Reaction
• Catalysis
  ADH1A → Biochemical Reaction

Edit history (2)

• 2022-09-26 Create
• 2022-09-26 Update Added link to PD pathway