About this pathway
Work in progress
Reactions & interactions (13)
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Biochemical Reaction
tamsulosin → demethyl tamsulosin glucuronide
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Biochemical Reaction
deethyltamsulosin → deethyltamsulosin sulfate
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Biochemical Reaction
tamsulosin → 2-ethoxyphenoxyacetic acid
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Biochemical Reaction
tamsulosin → deethyltamsulosin
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Biochemical Reaction
tamsulosin → tamsulosin metabolite M-2
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Biochemical Reaction
tamsulosin → tamsulosin metabolite M-3
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Biochemical Reaction
deethyltamsulosin → deethyltamsulosin glucuronide
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Catalysis
CYP2D6 → Biochemical Reaction
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Catalysis
CYP3A4 → Biochemical Reaction
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Catalysis
CYP3A4 → Biochemical Reaction
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Catalysis
CYP3A4 → Biochemical Reaction
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Catalysis
CYP2D6 → Biochemical Reaction
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Leads To
2-ethoxyphenoxyacetic acid → Interstitial Lung Diseases
Edit history (2)
- 2021-11-17 Note Discussion of PMID: 32316326 suggested that 2-ethoxyphenoxyacetic acid is the most toxic metabolite and therefore likely to contribute to drug induced lung damage, however did not give direct evidence.
- 2021-11-17 Create