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PharmGKB · ClinPGx

In Progress: Pyrazinamide Pathway, Pharmacokinetics

PA166271521 Last updated June 2022 Caroline F. Thorn
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Drugs & chemicals
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Conditions
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Reactions
In Progress: Pyrazinamide Pathway, Pharmacokinetics pathway diagram
In Progress: Pyrazinamide Pathway, Pharmacokinetics — pathway diagram from PharmGKB / ClinPGx
Click to enlarge

About this pathway

Work in progress...

Reactions & interactions (11)

  • Biochemical Reaction
    pyrazinoic acid → 5-hydroxypyrazinoic acid
  • Biochemical Reaction
    5-hydroxypyrazinamide → 5-hydroxypyrazinoic acid
  • Biochemical Reaction
    pyrazinamide → pyrazinoic acid
  • Biochemical Reaction
    pyrazinamide → 5-hydroxypyrazinamide
  • Catalysis
    XDH → Biochemical Reaction
  • Catalysis
    NAAA → Biochemical Reaction
  • Catalysis
    NAAA → Biochemical Reaction
  • Catalysis
    XDH → Biochemical Reaction
  • Catalysis
    AOX1 → Biochemical Reaction
  • Leads To
    pyrazinoic acid → Toxic liver disease
  • Leads To
    5-hydroxypyrazinoic acid → Toxic liver disease

Edit history (1)

  • 2022-06-13 Create
In Progress: Pyrazinamide Pathway, Pharmacokinetics pathway diagram (enlarged)