All PharmGKB pathways
PharmGKB · ClinPGx

In Progress: Sulfamethoxazole Pathway, Pharmacokinetics

PA166271461 Last updated June 2022 Caroline F. Thorn
1/5
Drugs & chemicals
0
Genes
2/2
Conditions
10
Reactions
In Progress: Sulfamethoxazole Pathway, Pharmacokinetics pathway diagram
In Progress: Sulfamethoxazole Pathway, Pharmacokinetics — pathway diagram from PharmGKB / ClinPGx
Click to enlarge

About this pathway

Work in progress...

Reactions & interactions (10)

  • Biochemical Reaction
    4-nitrososulfamethoxazole → nitrosulfamethoxazole
  • Biochemical Reaction
    sulfamethoxazole hydroxylamine → 4-nitrososulfamethoxazole
  • Biochemical Reaction
    sulfamethoxazole → sulfamethoxazole hydroxylamine
  • Biochemical Reaction
    4-nitrososulfamethoxazole → sulfamethoxazole hydroxylamine
  • Biochemical Reaction
    sulfamethoxazole → n-acetyl sulfamethoxazole
  • Catalysis
    MPO → Biochemical Reaction
  • Catalysis
    NAT2 → Biochemical Reaction
  • Catalysis
    NAT1 → Biochemical Reaction
  • Leads To
    protein adduct → Hypersensitivity
  • Leads To
    4-nitrososulfamethoxazole → protein adduct

Edit history (1)

  • 2022-06-13 Create
In Progress: Sulfamethoxazole Pathway, Pharmacokinetics pathway diagram (enlarged)