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PharmGKB · ClinPGx

In Progress: Dextromethorphan Pathway, Pharmacokinetics

PA166265501 Last updated March 2022 Caroline F. Thorn
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In Progress: Dextromethorphan Pathway, Pharmacokinetics pathway diagram
In Progress: Dextromethorphan Pathway, Pharmacokinetics — pathway diagram from PharmGKB / ClinPGx
Click to enlarge

About this pathway

Work in progress.

Reactions & interactions (11)

  • Biochemical Reaction
    dextrorphan → dextrorphan O-glucuronide
  • Biochemical Reaction
    dextromethorphan → dextrorphan
  • Biochemical Reaction
    3-methoxymorphinan → 3-hydroxymorphinan
  • Biochemical Reaction
    dextrorphan → 3-hydroxymorphinan
  • Biochemical Reaction
    dextromethorphan → 3-methoxymorphinan
  • Catalysis
    CYP2D6 → Biochemical Reaction
  • Catalysis
    CYP3A4 → Biochemical Reaction
  • Catalysis
    CYP2D6 → Biochemical Reaction
  • Catalysis
    CYP3A4 → Biochemical Reaction
  • Catalysis
    CYP3A4 → Biochemical Reaction
  • Catalysis
    CYP2B6 → Biochemical Reaction

Edit history (1)

  • 2022-03-01 Create
In Progress: Dextromethorphan Pathway, Pharmacokinetics pathway diagram (enlarged)